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Guatemala adopted science-based regulations for the adoption of agricultural biotechnology in 2018. These regulations were immediately challenged by activists but in 2021 the Supreme Court and Constitutional Court reaffirmed the legality of the regulatory process, paving the way for the approvals of the first applications in April 2021.

After over ten years, Serbia still has not implemented changes to its Law on Genetically Engineered Organisms (GEOs) which was adopted in 2009. The current law strictly prohibits the importation, production, or commercial growing of genetically engineered crops. The law does not conform to European Union (EU) regulations or the World Trade Organization (WTO) Sanitary and Phytosanitary (SPS) agreement.